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Flickering stimuli do not reliably induce visual hallucinations in Parkinson's disease

Weil, R; Zarkali, A; Lees, A; (2019) Flickering stimuli do not reliably induce visual hallucinations in Parkinson's disease. Journal of Parkinson's Disease , 9 (3) pp. 631-635. 10.3233/JPD-191635. Green open access

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Abstract

Visual hallucinations are a common and often distressing feature of Parkinson’s disease; they are ephemeral and capricious, making them difficult to study but tend to be more prominent in dim illumination. Flickering stimuli can induce simple hallucinations even in healthy individuals. We tested a stroboscope and an equivalent full-screen flickering stimulus in 16 participants: 7 patients with Parkinson’s and habitual visual hallucinations, 6 Parkinson’s patients without hallucinations and 3 controls. Both flicker sources induced varied geometrical hallucinations in 4 participants (25%) and complex hallucinations in 1 but neither induced typical Parkinson’s-associated hallucinations.

Type: Article
Title: Flickering stimuli do not reliably induce visual hallucinations in Parkinson's disease
Open access status: An open access version is available from UCL Discovery
DOI: 10.3233/JPD-191635
Publisher version: https://doi.org/10.3233/JPD-191635
Language: English
Additional information: This article is published online with Open Access and distributed under the terms of the Creative Commons Attribution License (CC-BY-4.0).https://creativecommons.org/licenses/by/4.0/
Keywords: Parkinson’s disease, visual hallucinations, stroboscopic light, hallucination state
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/10076136
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