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Respiration resolved imaging with continuous stable state 2D acquisition using linear frequency SWEEP

Jackson, LH; Price, AN; Hutter, J; Ho, A; Roberts, TA; Slator, PJ; Clough, JR; ... Hajnal, JV; + view all (2019) Respiration resolved imaging with continuous stable state 2D acquisition using linear frequency SWEEP. Magnetic Resonance in Medicine , 82 (5) pp. 1631-1645. 10.1002/mrm.27834. Green open access

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Abstract

PURPOSE: To investigate the potential of continuous radiofrequency (RF) shifting (SWEEP) as a technique for creating densely sampled data while maintaining a stable signal state for dynamic imaging. METHODS: We present a method where a continuous stable state of magnetization is swept smoothly across the anatomy of interest, creating an efficient approach to dense multiple 2D slice imaging. This is achieved by introducing a linear frequency offset to successive RF pulses shifting the excited slice by a fraction of the slice thickness with each successive repeat times (TR). Simulations and in vivo imaging were performed to assess how this affects the measured signal. Free breathing, respiration resolved 4D volumes in fetal/placental imaging is explored as potential application of this method. RESULTS: The SWEEP method maintained a stable signal state over a full acquisition reducing artifacts from unstable magnetization. Simulations demonstrated that the effects of SWEEP on slice profiles was of the same order as that produced by physiological motion observed with conventional methods. Respiration resolved 4D data acquired with this method shows reduced respiration artifacts and resilience to non-rigid and non-cyclic motion. CONCLUSIONS: The SWEEP method is presented as a technique for improved acquisition efficiency of densely sampled short-TR 2D sequences. Using conventional slice excitation the number of RF pulses required to enter a true steady state is excessively high when using short-TR 2D acquisitions, SWEEP circumvents this limitation by creating a stable signal state that is preserved between slices.

Type: Article
Title: Respiration resolved imaging with continuous stable state 2D acquisition using linear frequency SWEEP
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mrm.27834
Publisher version: https://doi.org/10.1002/mrm.27834
Language: English
Additional information: © 2019 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
Keywords: 4D, RF, angiography, fetal, free-breathing, placental, steady state
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10076020
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