Rashed, AN;
Tomlin, S;
Arenas-López, S;
Cavell, G;
Whittlesea, C;
(2019)
Evaluation of the practice of dose-rounding in paediatrics.
International Journal of Pharmacy Practice
10.1111/ijpp.12549.
(In press).
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Abstract
OBJECTIVES: To investigate the rounding of prescribed drug doses for paediatric administration. METHODS: A cross-sectional medication chart review was conducted at a UK paediatric hospital. Proposed administration dose volumes were calculated for prescribed doses using available manufactured liquids measured with oral and intravenous syringes. Resulting percentage deviations in doses administered were calculated. RESULTS: Of 2031 doses observed, 524 (25.8%) required rounding. The majority of which were for children aged 1-12 months. Twenty-seven rounded doses deviated from the prescribed dose by more than 10%. CONCLUSION: This study highlights the impact of dose-rounding in paediatrics and the need for standardisation.
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