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Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding

Singh, V; Guo, T; Xu, H; Wu, L; Gu, J; Wu, C; Gref, R; (2017) Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding. Chemical Communications , 53 (66) pp. 9246-9249. 10.1039/C7CC03471G. Green open access

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Abstract

A facile and one step-method was developed to enhance the water stability of CD-MOF nanoparticles through surface modification with cholesterol. CD-MOFs were able to maintain their cubic crystalline structures even after 24 h of incubation, well tolerated in vivo and could increase up to 4 times the blood half-life of DOX.

Type: Article
Title: Moisture resistant and biofriendly CD-MOF nanoparticles obtained via cholesterol shielding
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/C7CC03471G
Publisher version: https://doi.org/10.1039/C7CC03471G
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10075857
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