Reducing research waste through the standardisation of outcomes and definitions

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Reducing research waste through the standardisation of outcomes and definitions

Rogozińska, E; Eckert, LO; Khan, KS; (2019) Reducing research waste through the standardisation of outcomes and definitions. BJOG: An International Journal of Obstetrics and Gynaecology , 126 (3) pp. 308-309. 10.1111/1471-0528.15238. Green open access

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Abstract

The body of evidence indicating that the poor reporting of outcomes in research hinders progress in medicine is growing. For example, a systematic review of 79 randomised trials evaluating therapeutic interventions for pre‐eclampsia has identified 72 different maternal and 47 offspring outcomes.1 In addition to the lack of consensus regarding which outcomes to measure, there is also disagreement on which definitions or instruments to use for measurements.2 The authors of another study identified a lack of uniformity in the definition of maternal morbidities,3 that hinder comparisons of those conditions across countries.

Type:	Article
Title:	Reducing research waste through the standardisation of outcomes and definitions
Location:	England
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1111/1471-0528.15238
Publisher version:	https://doi.org/ 10.1111/1471-0528.15238
Language:	English
Additional information:	This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords:	Biomedical Research, Humans, Outcome Assessment (Health Care), Reference Standards
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI:	https://discovery.ucl.ac.uk/id/eprint/10075515