UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Quantitative pancreatic MRI: a pathology-based review.

Chouhan, MD; Firmin, L; Read, S; Amin, Z; Taylor, SA; (2019) Quantitative pancreatic MRI: a pathology-based review. British Journal of Radiology , 92 (1099) 10.1259/bjr.20180941. Green open access

[thumbnail of Taylor_Quantitative pancreatic MRI. A pathology-based review_AAM.pdf]
Preview
Text
Taylor_Quantitative pancreatic MRI. A pathology-based review_AAM.pdf - Accepted Version

Download (582kB) | Preview

Abstract

MRI plays an important role in the clinical management of pancreatic disorders and interpretation is reliant on qualitative assessment of anatomy. Conventional sequences capturing pancreatic structure can however be adapted to yield quantitative measures which provide more diagnostic information, with a view to increasing diagnostic accuracy, improving patient stratification, providing robust non-invasive outcome measures for therapeutic trials and ultimately personalizing patient care. In this review, we evaluate the use of established techniques such as secretin-enhanced MR cholangiopancreatography, diffusion-weighted imaging, T_{1}, T_{2}* and fat fraction mapping, but also more experimental methods such as MR elastography and arterial spin labelling, and their application to the assessment of diffuse pancreatic disease (including chronic, acute and autoimmune pancreatitis/IgG4 disease, metabolic disease and iron deposition disorders) and cystic/solid focal pancreatic masses. Finally, we explore some of the broader challenges to their implementation and future directions in this promising area.

Type: Article
Title: Quantitative pancreatic MRI: a pathology-based review.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1259/bjr.20180941
Publisher version: https://doi.org/10.1259/bjr.20180941
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10075311
Downloads since deposit
112Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item