Vazquez-Alfageme, C; Papastefanou, VP; Patel, PJ; Degli-Esposti, S; Cohen, VML; Sagoo, MS; (2019) Swept-Source OCT and Near-Infrared Reflectance Patterns in Choroidal Nevi. Ophthalmology Retina , 3 (5) pp. 429-435. 10.1016/j.oret.2019.01.001.

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Text SWEPT SOURCE OCT AND NEAR INFRARED REFLECTANCE PATTERNS IN CHOROIDAL NEVI Final MS.pdf - Accepted Version Download (10MB) | Preview

Abstract

PURPOSE: To describe the 3 distinct patterns of choroidal nevi in swept-source (SS) OCT and apply that classification to a cohort of consecutive choroidal nevi. Also, we aim to describe the findings of these lesions in near-infrared reflectance (NIR) at different wavelengths (820 and 1050 nm). DESIGN: Single-center, retrospective, observational study. PARTICIPANTS: One hundred four consecutive patients with choroidal nevi. METHODS: Retrospective analysis of choroidal nevi imaged with SS OCT and NIR. MAIN OUTCOME MEASURES: Lesions were classified according to OCT patterns as type A (high reflectivity with optical shadowing), type B (medium reflectivity with partial visualization of the scleral boundary), and type C (hyporeflective with complete visualization of the scleral boundary). RESULTS: Of 104 choroidal nevi, 97 lesions (93.3%) could be classified into 1 of the SS OCT patterns. Forty-nine percent corresponded to type A, 26% corresponded to type C, and 18.3% corresponded to type B. In NIR (n = 820), 76% of lesions were hyperreflective, whereas in NIR (n = 1050), most of the lesions were hyporeflective (59.6%; inverse reflectance). CONCLUSIONS: Choroidal nevi present distinct patterns according to SS OCT features. Clinical implications are yet to be determined. In NIR, inverse reflectance may be a consequence of the confocality of the device, rather than a property of the lesions.

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