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Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention

Petersen, E; Kantele, A; Koopmans, M; Asogun, D; Yinka-Ogunleye, A; Ihekweazu, C; Zumla, A; (2019) Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention. Infectious Disease Clinics of North America , 33 (4) pp. 1027-1043. 10.1016/j.idc.2019.03.001. Green open access

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Abstract

Recently, concern has been raised about the emergence of human monkeypox virus and the occasionally severe clinical presentation bearing resemblance to that of smallpox. In 2018 3 patients in the UK were diagnosed with monkeypox, and the frequency and geographic distribution of cases across West and Central Africa have increased in recent years. In Nigeria, most monkeypox patients are aged <40 years and lack cross-protective immunity because they were born after discontinuation of the smallpox eradication campaign. This article reviews the epidemiology, clinical features, and management of monkeypox and discusses its growing public health threat in this context.

Type: Article
Title: Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.idc.2019.03.001
Publisher version: https://doi.org/10.1016/j.idc.2019.03.001
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Monkeypox, Smallpox, West Africa, Epidemic
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10073997
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