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BK virus: Current understanding of pathogenicity and clinical disease in transplantation

Chong, S; Antoni, M; Macdonald, A; Reeves, M; Harber, M; Magee, C; (2019) BK virus: Current understanding of pathogenicity and clinical disease in transplantation. Reviews in Medical Virology , 29 (4) , Article e2044. 10.1002/rmv.2044. Green open access

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Abstract

BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.

Type: Article
Title: BK virus: Current understanding of pathogenicity and clinical disease in transplantation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/rmv.2044
Publisher version: https://doi.org/10.1002/rmv.2044
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: BK virus, transplantation, transplant virology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10071793
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