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Rapid task-dependent tuning of the mouse olfactory bulb

Koldaeva, A; Schaefer, AT; Fukunaga, I; (2019) Rapid task-dependent tuning of the mouse olfactory bulb. eLIFE , 8 , Article e43558. 10.7554/eLife.43558. Green open access

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Abstract

Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way.

Type: Article
Title: Rapid task-dependent tuning of the mouse olfactory bulb
Open access status: An open access version is available from UCL Discovery
DOI: 10.7554/eLife.43558
Publisher version: https://doi.org/10.7554/eLife.43558.001
Language: English
Additional information: © 2019, Koldaeva et al. This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: https://discovery.ucl.ac.uk/id/eprint/10071535
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