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Investigating Hepatitis C Virus Infection Using Super-Resolution Microscopy

Pereira, PM; Jacobs, C; Grove, J; (2019) Investigating Hepatitis C Virus Infection Using Super-Resolution Microscopy. Hepatitis C Virus Protocols: Methods in Molecular Biology , 1911 pp. 247-261. 10.1007/978-1-4939-8976-8_17. Green open access

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Grove_HCV SRM Methods Article JG 10.10.17.pdf - Accepted Version

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Grove_Figure 1 Localisation.pdf - Accepted Version

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Abstract

Super-resolution microscopy (SRM) can provide a window on the nanoscale events of virus replication. Here we describe a protocol for imaging hepatitis C virus-infected cells using localization SRM. We provide details on sample preparation, immunostaining, data collection, and super-resolution image reconstruction. We have made all efforts to generalize the protocol to make it accessible to all budding super-resolution microscopists.

Type: Article
Title: Investigating Hepatitis C Virus Infection Using Super-Resolution Microscopy
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-1-4939-8976-8_17
Publisher version: http://doi.org/10.1007/978-1-4939-8976-8_17
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Hepatitis, Imaging, Microscopy, Super-resolution, Virus
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10070969
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