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Computational modelling of interventions for developmental disorders

Thomas, MSC; Fedor, A; Davis, R; Yang, J; Alireza, H; Charman, T; Masterson, J; (2019) Computational modelling of interventions for developmental disorders. Psychological Review 10.1037/rev0000151. (In press). Green open access

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Abstract

We evaluate the potential of connectionist models of developmental disorders to offer insights into theefficacy of interventions. Based on a range of computational simulation results, we assess factors thatinfluence the effectiveness of interventions for reading, language, and other cognitive developmentaldisorders. The analysis provides a level of mechanistic detail that is generally lacking in behavioralapproaches to intervention. We review an extended program of modeling work in four sections. In thefirst, we consider long-term outcomes and the possibility of compensated outcomes and resolution ofearly delays. In the second section, we address methods to remediate atypical development in a singlenetwork. In the third section, we address interventions to encourage compensation via alternativepathways. In the final section, we consider the key issue of individual differences in response tointervention. Together with advances in understanding the neural basis of developmental disorders andneural responses to training, formal computational approaches can spur theoretical progress to narrow thegap between the theory and practice of intervention.

Type: Article
Title: Computational modelling of interventions for developmental disorders
Open access status: An open access version is available from UCL Discovery
DOI: 10.1037/rev0000151
Publisher version: https://doi.org/10.1037/rev0000151
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: computational modeling, connectionism, developmental disorders, intervention
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education
UCL > Provost and Vice Provost Offices > School of Education > UCL Institute of Education > IOE - Psychology and Human Development
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Language and Cognition
URI: https://discovery.ucl.ac.uk/id/eprint/10070376
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