Lam, CG;
Howard, SC;
Bouffet, E;
Pritchard-Jones, K;
(2019)
Science and health for all children with cancer.
Science
, 363
(6432)
pp. 1182-1186.
10.1126/science.aaw4892.
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Pritchard-Jones aaw 4892 Science and Health for All Children with Cancer 2019 2 9 Submitted.pdf - Accepted Version Download (1MB) | Preview |
Abstract
Each year approximately 429,000 children and adolescents aged 0-19 years are expected to develop cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in highincome countries (HIC), but are less than 30% for the 384,000 children in low- and middle-income countries (LMIC). Improved survival rates in HIC have been achieved through multidisciplinary care and research, with treatment regimens utilizing mostly generic medicines and optimized risk stratification. Children’s outcomes in LMIC can be improved by adapting effective treatments to local resources and clinical needs, and addressing common problems such as delayed diagnosis and treatment abandonment. By supporting local leaders to increase service capacity and achieve measurable clinical improvements, collaborative partnerships can stimulate governmental and nongovernmental investments. These approaches should bring the new WHO childhood cancer survival target of 60% within reach of all by 2030.
Type: | Article |
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Title: | Science and health for all children with cancer |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1126/science.aaw4892 |
Publisher version: | https://doi.org/10.1126/science.aaw4892 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
URI: | https://discovery.ucl.ac.uk/id/eprint/10070258 |
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