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Cardiac troponins and prediction of coronary artery disease risk

Shah, AD; (2016) Cardiac troponins and prediction of coronary artery disease risk. [Editorial comment]. Heart , 102 (15) pp. 1153-1154. 10.1136/heartjnl-2015-309241. Green open access

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Abstract

Cardiac troponins are released into the bloodstream as a result of myocardial injury and their detection in the blood is in routine clinical use for the diagnosis of myocardial infarction. A range of other cardiac and non-cardiac conditions may also cause a rise in troponin. A number of recent studies have found that high-sensitivity troponin is significantly associated with future coronary events in people without prior cardiovascular disease. Some studies have investigated its incremental benefit in risk prediction models, but have been too small to show a statistically significant improvement in the C statistic. Nevertheless, troponin measurements should be considered as a cardiovascular risk marker among healthy people as well as a diagnostic marker for myocardial infarction.

Type: Article
Title: Cardiac troponins and prediction of coronary artery disease risk
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/heartjnl-2015-309241
Publisher version: http://doi.org/10.1136/heartjnl-2015-309241
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery.ucl.ac.uk/id/eprint/10067366
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