Shah, AD;
(2016)
Cardiac troponins and prediction of coronary artery disease risk.
[Editorial comment].
Heart
, 102
(15)
pp. 1153-1154.
10.1136/heartjnl-2015-309241.
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Abstract
Cardiac troponins are released into the bloodstream as a result of myocardial injury and their detection in the blood is in routine clinical use for the diagnosis of myocardial infarction. A range of other cardiac and non-cardiac conditions may also cause a rise in troponin. A number of recent studies have found that high-sensitivity troponin is significantly associated with future coronary events in people without prior cardiovascular disease. Some studies have investigated its incremental benefit in risk prediction models, but have been too small to show a statistically significant improvement in the C statistic. Nevertheless, troponin measurements should be considered as a cardiovascular risk marker among healthy people as well as a diagnostic marker for myocardial infarction.
Type: | Article |
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Title: | Cardiac troponins and prediction of coronary artery disease risk |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1136/heartjnl-2015-309241 |
Publisher version: | http://doi.org/10.1136/heartjnl-2015-309241 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics |
URI: | https://discovery.ucl.ac.uk/id/eprint/10067366 |
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