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Thinking through acidic Ca2+ stores

Patel, S; Brailoiu, E; (2018) Thinking through acidic Ca2+ stores. Science Signaling , 11 (558) , Article eaau3342. 10.1126/scisignal.aau3342. Green open access

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Abstract

Glutamate signaling regulates neuronal activity and synaptic plasticity, which underlies learning and memory. In this issue of Science Signaling, Foster et al. found that metabotropic glutamate receptors mediate long-term potentiation in hippocampal neurons by mobilizing acidic endolysosomal Ca2+ stores through the intracellular messenger NAADP.

Type: Article
Title: Thinking through acidic Ca2+ stores
Open access status: An open access version is available from UCL Discovery
DOI: 10.1126/scisignal.aau3342
Publisher version: https://doi.org/10.1126/scisignal.aau3342
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/10066861
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