Vicari, S;
Piccini, G;
Mercuri, E;
Battini, R;
Chieffo, D;
Bulgheroni, S;
Pecini, C;
... Alfieri, P; + view all
(2018)
Implicit learning deficit in children with Duchenne muscular dystrophy: Evidence for a cerebellar cognitive impairment?
PLoS One
, 13
(1)
, Article e0191164. 10.1371/journal.pone.0191164.
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Abstract
This study aimed at comparing implicit sequence learning in individuals affected by Duchenne Muscular Dystrophy without intellectual disability and age-matched typically developing children. A modified version of the Serial Reaction Time task was administered to 32 Duchenne children and 37 controls of comparable chronological age. The Duchenne group showed a reduced rate of implicit learning even if in the absence of global intellectual disability. This finding provides further evidence of the involvement of specific aspects of cognitive function in Duchenne muscular dystrophy and on its possible neurobiological substrate.
| Type: | Article |
|---|---|
| Title: | Implicit learning deficit in children with Duchenne muscular dystrophy: Evidence for a cerebellar cognitive impairment? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1371/journal.pone.0191164 |
| Publisher version: | https://doi.org/10.1371/journal.pone.0191164 |
| Language: | English |
| Additional information: | © 2018 Vicari et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). |
| Keywords: | Learning, Cerebellum, Children, Learning disabilities, Cognitive impairment, Mutation, Reaction time, Duchenne muscular dystrophy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10066591 |
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