Heine, K;
Beskos, A;
Jasra, A;
Balding, D;
De Iorio, M;
(2018)
Bridging trees for posterior inference on ancestral recombination graphs.
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
, 474
(2220)
, Article 20180568. 10.1098/rspa.2018.0568.
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Abstract
We present a new Markov chain Monte Carlo algorithm, implemented in the software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelization.
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