Heine, K;
              
      
            
                Beskos, A;
              
      
            
                Jasra, A;
              
      
            
                Balding, D;
              
      
            
                De Iorio, M;
              
      
        
        
  
(2018)
  Bridging trees for posterior inference on ancestral recombination graphs.
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
, 474
       (2220)
    
    
    
    , Article 20180568.     10.1098/rspa.2018.0568.
  
  
      
    
  
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 Beskos_Bridging trees for posterior inference on ancestral recombination graphs_AAM.pdf - Accepted Version Download (631kB) | Preview  | 
          
Abstract
We present a new Markov chain Monte Carlo algorithm, implemented in the software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic processes, in which the local computations within a bridge can proceed independently of the rest of the DNA sequence, facilitating large-scale parallelization.
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