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The Age-Well observational study on expert meditators in the Medit-Ageing European project

Lutz, A; Klimecki, OM; Collette, F; Poisnel, G; Arenaza-Urquijo, E; Marchant, NL; De La Sayette, V; ... Chételat, G; + view all (2018) The Age-Well observational study on expert meditators in the Medit-Ageing European project. Alzheimer's and Dementia: Translational Research and Clinical Interventions , 4 pp. 756-764. 10.1016/j.trci.2018.11.002. Green open access

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Abstract

Introduction: The Age-Well observational, cross-sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD). Methods: Thirty cognitively unimpaired individuals aged 65 years or older with at least 10,000 hours of practice in mindfulness meditation (MM) and loving-kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long-term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age-Well randomized controlled trial. Results Recruitment and data collection began in late 2016 and will be completed by late 2019. Discussion: Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age-Well randomized controlled trial. These finding will contribute to the design of meditation-based prevention randomized controlled trials for the aged population and to the exploration of the possible long-time developmental trajectory of meditation training.

Type: Article
Title: The Age-Well observational study on expert meditators in the Medit-Ageing European project
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.trci.2018.11.002
Publisher version: https://doi.org/10.1016/j.trci.2018.11.002
Language: English
Additional information: Copyright © 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Aging, Alzheimer's disease, Dementia, Prevention, Cognition, Reserve, Meditation expertise, Mindfulness meditation, Compassion and loving-kindness meditation, Emotion, Lifestyle, Neuroimaging, Blood markers, Sleep
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/10065791
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