UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics

Finkel, RS; Mercuri, E; Meyer, OH; Simonds, AK; Schroth, MK; Graham, RJ; Kirschner, J; ... Sejersen, T; + view all (2018) Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics. Neuromuscular Disorders , 28 (3) pp. 197-207. 10.1016/j.nmd.2017.11.004. Green open access

[thumbnail of Muntoni_OA_1-s2.0-S0960896617312907-main.pdf]
Preview
Text
Muntoni_OA_1-s2.0-S0960896617312907-main.pdf - Published Version

Download (717kB) | Preview

Abstract

This is the second half of a two-part document updating the standard of care recommendations for spinal muscular atrophy published in 2007. This part includes updated recommendations on pulmonary management and acute care issues, and topics that have emerged in the last few years such as other organ involvement in the severe forms of spinal muscular atrophy and the role of medications. Ethical issues and the choice of palliative versus supportive care are also addressed. These recommendations are becoming increasingly relevant given recent clinical trials and the prospect that commercially available therapies will likely change the survival and natural history of this disease.

Type: Article
Title: Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.nmd.2017.11.004
Publisher version: https://doi.org/10.1016/j.nmd.2017.11.004
Language: English
Additional information: Copyright © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Spinal muscular atrophy, Care, Pulmonary, Acute, Nutrition
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10065764
Downloads since deposit
703Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item