Finkel, RS;
Mercuri, E;
Meyer, OH;
Simonds, AK;
Schroth, MK;
Graham, RJ;
Kirschner, J;
... Sejersen, T; + view all
(2018)
Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics.
Neuromuscular Disorders
, 28
(3)
pp. 197-207.
10.1016/j.nmd.2017.11.004.
Preview |
Text
Muntoni_OA_1-s2.0-S0960896617312907-main.pdf - Published Version Download (717kB) | Preview |
Abstract
This is the second half of a two-part document updating the standard of care recommendations for spinal muscular atrophy published in 2007. This part includes updated recommendations on pulmonary management and acute care issues, and topics that have emerged in the last few years such as other organ involvement in the severe forms of spinal muscular atrophy and the role of medications. Ethical issues and the choice of palliative versus supportive care are also addressed. These recommendations are becoming increasingly relevant given recent clinical trials and the prospect that commercially available therapies will likely change the survival and natural history of this disease.
Type: | Article |
---|---|
Title: | Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.nmd.2017.11.004 |
Publisher version: | https://doi.org/10.1016/j.nmd.2017.11.004 |
Language: | English |
Additional information: | Copyright © 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
Keywords: | Spinal muscular atrophy, Care, Pulmonary, Acute, Nutrition |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept |
URI: | https://discovery.ucl.ac.uk/id/eprint/10065764 |
Archive Staff Only
![]() |
View Item |