Chiesa, ST;
Papageorgiou, N;
Charakida, M;
(2017)
Statins in Peripheral Arterial Disease.
Current Pharmaceutical Design
, 23
(46)
pp. 7099-7108.
10.2174/1381612823666170926130826.
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Abstract
Peripheral arterial disease (PAD) is a common atherosclertico condition affecting the lower extremities. PAD patients share similar cardiovascular risk factors to coronary artery disease patients and suffer from increased cardiovascular morbidity and mortality. Statins have been widely used in coronary artery disease patients but have been underused in patients with PAD. In the current review, we present data which support the beneficial role of statins in both reducing cardiovascular events and improving symptom-related outcomes in PAD patients. Alongside their lipid lowering effects, their pleiotropic actions are also discussed. Recent guidelines, which strongly recommend the administration of statins in PAD patients, are also presented.
| Type: | Article |
|---|---|
| Title: | Statins in Peripheral Arterial Disease |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.2174/1381612823666170926130826 |
| Publisher version: | https://doi.org/10.2174/1381612823666170926130826 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Statins, outcomes, peripheral arterial disease, pleiotropic effects, atherosclertico condition. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10065752 |
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