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Low aspirin use and high prevalence of pre-eclampsia risk factors among pregnant women in a multinational SLE inception cohort

Mendel, A; Bernatsky, SB; Hanly, JG; Urowitz, MB; Clarke, AE; Romero-Diaz, J; Gordon, C; ... Vinet, É; + view all (2019) Low aspirin use and high prevalence of pre-eclampsia risk factors among pregnant women in a multinational SLE inception cohort. Annals of the Rheumatic Diseases 10.1136/annrheumdis-2018-214434. (In press). Green open access

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Abstract

Women with systemic lupus erythematosus (SLE) carry a substantially higher risk for preeclampsia compared to the general population [1]. Aspirin reduces the risk of preeclampsia in high-risk pregnancies by more than half [2] and thus is recommended in SLE [3-5]. The European League Against Rheumatism highlights the need for aspirin in SLE pregnancies, particularly in those with nephritis or positive antiphospholipid antibodies (aPL) [5]. Despite this, little is known about current practice. Therefore, we assessed the prevalence of aspirin use in SLE pregnancies within the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort, which has been described elsewhere.

Type: Article
Title: Low aspirin use and high prevalence of pre-eclampsia risk factors among pregnant women in a multinational SLE inception cohort
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/annrheumdis-2018-214434
Publisher version: http://dx.doi.org/10.1136/annrheumdis-2018-214434
Language: English
Additional information: Copyright © Author(s) (or their employer(s) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10065137
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