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Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo

Pavelic, SK; Medica, JS; Gumbarevic, D; Filosevic, A; Przulj, N; Pavelic, K; (2018) Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo. Frontiers in Pharmacology , 9 , Article 1350. 10.3389/fphar.2018.01350. Green open access

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Abstract

Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes. Recently, a more specific application of one naturally occurring zeolite material, clinoptilolite, has been widely studied in veterinary and human medicine. Due to a number of positive effects on health, including detoxification properties, the usage of clinoptilolite-based products in vivo has increased enormously. However, concerns have been raised in the public about the safety of clinoptilolite materials for in vivo applications. Here, we review the scientific literature on the health effects and safety in medical applications of different clinoptilolite-based materials and propose some comprehensive, scientifically-based hypotheses on possible biological mechanisms underlying the observed effects on the health and body homeostasis. We focus on the safety of the clinoptilolite material and the positive medical effects related to detoxification, immune response, and the general health status.

Type: Article
Title: Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo
Open access status: An open access version is available from UCL Discovery
DOI: 10.3389/fphar.2018.01350
Publisher version: https://doi.org/10.3389/fphar.2018.01350
Language: English
Additional information: © 2018 Kraljević Pavelić, Simović Medica, Gumbarević, Filošević, Pržulj and Pavelić. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: zeolite, clinoptilolite, toxicology, immunostimulation, antioxidant properties
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10064898
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