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Life as a guide to prebiotic nucleotide synthesis

Harrison, SA; Lane, N; (2018) Life as a guide to prebiotic nucleotide synthesis. Nature Communications , 9 , Article 5176. 10.1038/s41467-018-07220-y. Green open access

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Abstract

Synthesis of activated nucleotides has been accomplished under ‘prebiotically plausible’ conditions, but bears little resemblance to the chemistry of life as we know it. Here we argue that life is an indispensable guide to its own origins.

Type: Article
Title: Life as a guide to prebiotic nucleotide synthesis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41467-018-07220-y
Publisher version: https://doi.org/10.1038/s41467-018-07220-y
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/10064340
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