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High signal contrast gating with biomodified Gd doped mesoporous nanoparticles

Huang, W-Y; Davies, G-L; Davis, JJ; (2012) High signal contrast gating with biomodified Gd doped mesoporous nanoparticles. Chemical Communications , 49 (1) pp. 60-62. 10.1039/c2cc37545a. Green open access

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Abstract

Internally Gd doped mesoporous nanoparticles have been prepared and exhibit unprecedented relaxivities that are retained on external biomodification. In tuning diffusive water access, image contrast can be reversibly switched in the presence of a specific protein target.

Type: Article
Title: High signal contrast gating with biomodified Gd doped mesoporous nanoparticles
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c2cc37545a
Publisher version: https://doi.org/10.1039/c2cc37545a
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, SILICA NANOPARTICLES, SERUM-ALBUMIN, AGENTS, RELAXIVITY, GADOLINIUM, BINDING, STREPTAVIDIN, SCATTERING, DYNAMICS, DETECTS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10063838
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