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The mountainous Cretan dietary patterns and their relationship with cardiovascular risk factors: the Hellenic Isolated Cohorts MANOLIS study

Farmaki, A-E; Rayner, NW; Matchan, A; Spiliopoulou, P; Gilly, A; Kariakli, V; Kiagiadaki, C; ... Dedoussis, G; + view all (2016) The mountainous Cretan dietary patterns and their relationship with cardiovascular risk factors: the Hellenic Isolated Cohorts MANOLIS study. Public Health Nutrition , 20 (6) pp. 1063-1074. 10.1017/S1368980016003207. Green open access

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Abstract

Objective We carried out de novo recruitment of a population-based cohort (MANOLIS study) and describe the specific population, which displays interesting characteristics in terms of diet and health in old age, through deep phenotyping. Design Cross-sectional study where anthropometric, biochemical and clinical measurements were taken in addition to interview-based completion of an extensive questionnaire on health and lifestyle parameters. Dietary patterns were derived through principal component analysis based on a validated FFQ. Setting Geographically isolated Mylopotamos villages on Mount Idi, Crete, Greece. Subjects Adults (n 1553). Results Mean age of the participants was 61·6 years and 55·8 % were women. Of the population, 82·7 % were overweight or obese with a significantly different prevalence between overweight men and women (43·4 v. 34·7 %, P=0·002). The majority (70·6 %) of participants were married, while a larger proportion of women were widowed than men (27·8 v. 3·5 %, P<0·001). Smoking was more prevalent in men (38·7 v. 8·2 %, P<0·001), as 88·8% of women had never smoked. Four dietary patterns emerged as characteristic of the population; these were termed ‘local’, ‘high fat and sugar, ‘Greek café/tavern’ and ‘olive oil, fruits and vegetables’. Individuals more adherent to the local dietary pattern presented higher blood glucose (β=4·026, P<0·001). Similarly, individuals with higher compliance with the Greek café/tavern pattern had higher waist-to-hip ratio (β=0·012, P<0·001), blood pressure (β=1·015, P=0·005) and cholesterol (β=5·398, P<0·001). Conclusions Profiling of the MANOLIS elderly population identifies unique unhealthy dietary patterns that are associated with cardiometabolic indices.

Type: Article
Title: The mountainous Cretan dietary patterns and their relationship with cardiovascular risk factors: the Hellenic Isolated Cohorts MANOLIS study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S1368980016003207
Publisher version: https://doi.org/10.1017/S1368980016003207
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Public, Environmental & Occupational Health, Nutrition & Dietetics, Dietary patterns, Cardiovascular risk, Isolated population, Hellenic Isolated Cohorts, Crete, ARTERIAL-BLOOD PRESSURE, CORONARY-HEART-DISEASE, LIFE-STYLE FACTORS, MEDITERRANEAN DIET, OLIVE OIL, METABOLIC SYNDROME, FATTY-ACIDS, GREEK POPULATION, SERUM-LIPIDS, 7 COUNTRIES
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
URI: https://discovery.ucl.ac.uk/id/eprint/10063814
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