Haller, SPW;
Mills, KL;
Hartwright, CE;
David, AS;
Cohen Kadosh, K;
(2018)
When change is the only constant: The promise of longitudinal neuroimaging in understanding social anxiety disorder.
Developmental Cognitive Neuroscience
, 33
pp. 73-82.
10.1016/j.dcn.2018.05.005.
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Abstract
Longitudinal studies offer a unique window into developmental change. Yet, most of what we know about the pathophysiology of psychiatric disorders is based on cross-sectional work. Here, we highlight the importance of adopting a longitudinal approach in order to make progress towards identifying the neurobiological mechanisms of social anxiety disorder (SAD). Using examples, we illustrate how longitudinal data can uniquely inform SAD etiology and timing of interventions. The brain's inherently adaptive quality requires that we model risk correlates of disorders as dynamic in their expression. Developmental theories regarding timing of environmental events, cascading effects and (mal)adaptations of the developing brain will be crucial components of comprehensive, integrative models of SAD. We close by discussing analytical considerations when working with longitudinal, developmental data.
| Type: | Article |
|---|---|
| Title: | When change is the only constant: The promise of longitudinal neuroimaging in understanding social anxiety disorder |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.dcn.2018.05.005 |
| Publisher version: | https://doi.org/10.1016/j.dcn.2018.05.005 |
| Language: | English |
| Additional information: | Copyright © 2018 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/BY-NC-ND/4.0/). |
| Keywords: | Adolescence, Development, Longitudinal imaging, Psychopathology, Social anxiety, fMRI, Brain Mapping, Cross-Sectional Studies, Female, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Male, Neuroimaging, Phobia, Social |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10063446 |
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