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HIV Treatment Substantially Decreases Hospitalization Rates: Evidence From Rural South Africa

Hontelez, JAC; Bor, J; Tanser, FC; Pillay, D; Moshabela, M; Bärnighausen, T; (2018) HIV Treatment Substantially Decreases Hospitalization Rates: Evidence From Rural South Africa. Health Affairs , 37 (6) pp. 997-1004. 10.1377/hlthaff.2017.0820. Green open access

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Abstract

The effect of HIV treatment on hospitalization rates for HIV-infected people has never been established. We quantified this effect in a rural South African community for the period 2009–13. We linked clinical data on HIV treatment start dates for more than 2,000 patients receiving care in the public-sector treatment program with five years of longitudinal data on self-reported hospitalizations from a community-based population cohort of more than 100,000 adults. Hospitalization rates peaked during the first year of treatment and were about five times higher, compared to hospitalization rates after four years on treatment. Earlier treatment initiation could save more than US$300,000 per 1,000 patients over the first four years of HIV treatment, freeing up scarce resources. Future studies on the cost-effectiveness of HIV treatment should include these effects.

Type: Article
Title: HIV Treatment Substantially Decreases Hospitalization Rates: Evidence From Rural South Africa
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1377/hlthaff.2017.0820
Publisher version: https://doi.org/10.1377/hlthaff.2017.0820
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Assisted Reproductive Technology, HIV/AIDS, HIV Treatment, Antiretroviral Drugs, Hospital Cost, Confidence Intervals, Cost-effective
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10063217
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