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Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

Janicki, MJ; Roberts, SJ; Šponer, J; Powner, MW; Góra, RW; Szabla, R; (2018) Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments. Chemical Communications , 54 (95) pp. 13407-13410. 10.1039/c8cc07343k. Green open access

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Abstract

Pentose aminooxazolines and oxazolidinone thiones are considered as the key precursors which could have enabled the formation of RNA nucleotides under the conditions of early Earth. UV-irradiation experiments and quantum-chemical calculations demonstrate that these compounds are remarkably photostable and could accumulate over long periods of time in UV-rich prebiotic environments to undergo stereoisomeric purification.

Type: Article
Title: Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c8cc07343k
Publisher version: https://doi.org/10.1039/C8CC07343K
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10061892
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