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Exploring the Effects of Acute Sub-Anaesthetic Ketamine on Cognitive Function

Trotman, Catherine; (2018) Exploring the Effects of Acute Sub-Anaesthetic Ketamine on Cognitive Function. Doctoral thesis (D.Clin.Psy), UCL (University College London). Green open access

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Abstract

Part 1 of this thesis is a qualitative narrative systematic literature review which examines how the administration of acute sub-anaesthetic ketamine affects cognitive function in non-healthy patients in medical and psychiatric settings. Ten studies were included in the review, and study quality, the effect of ketamine on cognition, and ketamine’s effect on the medical and psychiatric problems identified is discussed. Part 2 describes a study of chronic pain patients receiving either acute subanaesthetic intravenous ketamine or lidocaine. It measures participant pain and cognitive performance before and after drug administration, and explores the relationships between pain, cognition and the drugs administered. This was a joint project carried out by two UCL Doctorate in Clinical Psychology trainees. The partner project evaluates the effect of ketamine on mood. All work was completed jointly by the two researchers. Finally, Part 3 of this thesis, the Critical Appraisal, discusses the process of completing this piece of research.

Type: Thesis (Doctoral)
Qualification: D.Clin.Psy
Title: Exploring the Effects of Acute Sub-Anaesthetic Ketamine on Cognitive Function
Event: UCL
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author 2018. Original content in this thesis is licensed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/by/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms.
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10061579
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