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New insights into phosphate homeostasis

Marks, J; Debnam, E; Unwin, R; (2009) New insights into phosphate homeostasis. British Journal of Renal Medicine , 14 (1) pp. 4-7. Green open access

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Abstract

Extracellular phosphate is crucial for many bodily functions, including skeletal development, energy metabolism, cell signalling and the regulation of protein synthesis. Body phosphate homeostasis is determined by the regulation of intestinal uptake of dietary phosphate, renal phosphate reabsorption and the exchange of phosphate between extracellular and bone storage pools. On a day-to-day basis, phosphate balance is achieved largely through the control of phosphate reabsorption in the proximal tubule: in the steady state, renal phosphate excretion reflects dietary intake, and daily urinary phosphate excretion correlates with its absorption from the diet.

Type: Article
Title: New insights into phosphate homeostasis
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.bjrm.co.uk/_year_search_review.aspx?JID...
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10061458
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