Cheung, ACM;
Díaz-Santín, LM;
(2018)
Share and share alike: the role of Tra1 from the SAGA and NuA4 coactivator complexes.
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pp. 1-7.
10.1080/21541264.2018.1530936.
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Abstract
SAGA and NuA4 are coactivator complexes required for transcription on chromatin. Although they contain different enzymatic and biochemical activities, both contain the large Tra1 subunit. Recent electron microscopy studies have resolved the complete structure of Tra1 and its integration in SAGA/NuA4, providing important insight into Tra1 function.
Type: | Article |
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Title: | Share and share alike: the role of Tra1 from the SAGA and NuA4 coactivator complexes |
Location: | United States |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1080/21541264.2018.1530936 |
Publisher version: | https://doi.org/10.1080/21541264.2018.1530936 |
Language: | English |
Additional information: | © 2018 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Keywords: | Chromatin and transcription, Eukaryotic transcription, NuA4, SAGA, Tra1, Transcription factors and co-activators, activator, coactivator, histone acetylation |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
URI: | https://discovery.ucl.ac.uk/id/eprint/10061029 |
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