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Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP)

Singh, RB; Agarwal, A; Agrawal, R; Sagoo, MS; Aggarwal, K; Gupta, V; (2019) Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP). In: Gupta, V and Nguyen, QD and LeHoang, P and Herbort, CPH, (eds.) The Uveitis Atlas. Springer: New Delhi, India. (In press). Green open access

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Abstract

Bilateral diffuse uveal melanocytic proliferation (BDUMP) is a rare paraneoplastic syndrome characterized by multiple subretinal, round, red patches in the retinal pigment epithelium; hyperfluorescence on fluorescein angiography; multiple elevated pigmented and nonpigmented uveal melanocytic tumors with diffuse uveal tract thickening; exudative retinal detachments; and rapid cataract development leading to progressive loss of vision. BDUMP is predictive of an occult or undiagnosed systemic malignancies and a marker for poor prognosis. The index chapter describes an illustrative case of BDUMP with multimodal imaging.

Type: Book chapter
Title: Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP)
ISBN-13: 978-81-322-2410-5
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-81-322-2506-5_105-1
Publisher version: https://doi.org/10.1007/978-81-322-2506-5_105-1
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Paraneoplastic syndrome, Bilateral diffuse uveal melanocytic proliferation, Melanocytic tumors, Uveal tumors, BDUMP, Melanocytes, Melanoma, Uvea
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10060442
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