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Novel usage of microfocus computed tomography (micro-CT) for visualisation of human embryonic development-Implications for future non-invasive post-mortem investigation

Shelmerdine, SC; Hutchinson, JC; Kang, X; Suich, JD; Ashworth, M; Cannie, MM; Segers, V; ... Arthurs, OJ; + view all (2018) Novel usage of microfocus computed tomography (micro-CT) for visualisation of human embryonic development-Implications for future non-invasive post-mortem investigation. Prenatal Diagnosis , 38 (7) pp. 538-542. 10.1002/pd.5281. Green open access

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Abstract

What's already known about this topic? Accurate pathological assessment of small gestational age fetuses is challenging. Dating an embryo/fetus is essential to recognise expected human developmental stages and prevent misdiagnosis. What does this study add? Micro‐CT offers a non‐destructive, digital method for dating human embryos. The micro‐CT imaging here is of the earliest gestation human embryo published to date with corresponding pathology. It can provide an alternative to autopsy even at early stages of development.

Type: Article
Title: Novel usage of microfocus computed tomography (micro-CT) for visualisation of human embryonic development-Implications for future non-invasive post-mortem investigation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/pd.5281
Publisher version: https://doi.org/10.1002/pd.5281
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Genetics & Heredity, Obstetrics & Gynecology, CONVENTIONAL AUTOPSY, FETAL, ACCEPTANCE
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10058452
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