Tornic, J;
Panicker, JN;
(2018)
The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis.
Current Neurology and Neuroscience Reports
, 18
(8)
, Article 54. 10.1007/s11910-018-0857-z.
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Abstract
Purpose of Review Multiple sclerosis (MS) is the most frequent neuroinflammatory disease of the central nervous system and is commonly associated with lower urinary tract (LUT) dysfunction. As a consequence, health-related quality of life is often impaired and the upper urinary tract might be at risk for damage. The aim of this review is to give an overview of current treatment options for LUT dysfunction in patients with MS. Recent Findings The treatment is tailored to the type of dysfunction—storage or voiding dysfunction—beginning with conservative treatment options and ending with invasive therapies and surgery. Additionally, alternative options, e.g., different intravesical therapies or cannabinoids, have been evaluated in recent years with promising results. Summary Current available therapies offer different possible treatments for LUT dysfunction in patients with MS. They address either voiding or storage dysfunction and therefore ameliorate LUT symptoms improve quality of life and protect the upper urinary tract.
| Type: | Article |
|---|---|
| Title: | The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s11910-018-0857-z |
| Publisher version: | https://doi.org/10.1007/s11910-018-0857-z |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Neurosciences, Neurosciences & Neurology, Review, Neurogenic lower urinary tract dysfunction, Neurogenic bladder treatment, Incontinence, Retention, Multiple sclerosis, NEUROGENIC DETRUSOR OVERACTIVITY, SPINAL-CORD-INJURY, TIBIAL NERVE-STIMULATION, QUALITY-OF-LIFE, DOUBLE-BLIND, SACRAL NEUROMODULATION, BLADDER DYSFUNCTION, INTERMITTENT CATHETERIZATION, ELECTRICAL-STIMULATION, ERECTILE DYSFUNCTION |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10057402 |
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