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Night work and risk of common mental disorders: Analyzing observational data as a non-randomized pseudo trial

Beltagy, MS; Pentti, J; Vahtera, J; Kivimäki, M; (2018) Night work and risk of common mental disorders: Analyzing observational data as a non-randomized pseudo trial. Scandinavian Journal of Work, Environment and Health , 44 (5) pp. 512-520. 10.5271/sjweh.3733. Green open access

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Abstract

OBJECTIVES: The aim of this study was to examine the status of night work as a risk factor for common mental disorders (CMD). METHODS: A cohort study with three data waves was conducted on populations of social and healthcare employees for a duration of eight years (total N=46 010). Data were analyzed as a non-randomized pseudo trial to examine (i) whether moving from non-night work to night work is associated with the development of CMD, (ii) the extent to which moving back to non-night work biases this association and (iii) whether moving from night to non-night work is associated with the recovery from CMD. RESULTS: According to logistic regression with generalized estimating equation and without bias-correction, changing to night work was not associated with the odds of acquiring CMD [odds ratio (OR) 1.03, 95% confidence interval (CI) 0.82–1.30]. However, night workers with CMD had higher odds of recovery from CMD when changing to non-night work compared to continuing night work (1.99, 95% CI 1.20–3.28). When night workers developed CMD, the odds of moving back to non-night work increased by 68%. In analyses corrected for this bias, changing from non-night to night work was associated with a 1.25-fold (95% CI 1.03–1.52) increased odds of acquiring CMD. CONCLUSIONS: A change from non-night to night work may increase the risk of CMD, while moving back from night to non-night work increased recovery from CMD.

Type: Article
Title: Night work and risk of common mental disorders: Analyzing observational data as a non-randomized pseudo trial
Open access status: An open access version is available from UCL Discovery
DOI: 10.5271/sjweh.3733
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. https://creativecommons.org/licenses/by/4.0/
Keywords: anxiety; common mental disorder; depression; mental disorder; mental health; night work; non-randomized pseudo trial; observational data; occupational health; shift work; shift worker; stress; working hour
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10056820
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