UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Fast adaptive optics scanning light ophthalmoscope retinal montaging

Davidson, B; Kalitzeos, A; Carroll, J; Dubra, A; Ourselin, S; Michaelides, M; Bergeles, C; (2018) Fast adaptive optics scanning light ophthalmoscope retinal montaging. Biomedical Optics Express , 9 (9) pp. 4317-4328. 10.1364/BOE.9.004317. Green open access

[thumbnail of Davidson_Fast adaptive.pdf]
Preview
Text
Davidson_Fast adaptive.pdf - Published Version

Download (15MB) | Preview

Abstract

The field of view of high-resolution ophthalmoscopes that require the use of adaptive optics (AO) wavefront correction is limited by the isoplanatic patch of the eye, which varies across individual eyes and with the portion of the pupil used for illumination and/or imaging. Therefore all current AO ophthalmoscopes have small fields of view comparable to, or smaller than, the isoplanatic patch, and the resulting images have to be stitched off-line to create larger montages. These montages are currently assembled either manually, by expert human graders, or automatically, often requiring several hours per montage. This arguably limits the applicability of AO ophthalmoscopy to studies with small cohorts and moreover, prevents the ability to review a real-time captured montage of all locations during image acquisition to further direct targeted imaging. In this work, we propose stitching the images with our novel algorithm, which uses oriented fast rotated brief (ORB) descriptors, local sensitivity hashing, and by searching for a ‘good enough’ transformation, rather than the best possible, to achieve processing times of 1-2 minutes per montage of 250 images. Moreover, the proposed method produces montages which are as accurate as previous methods, when considering the image similarity metrics: normalised mutual information (NMI), and normalised cross correlation (NCC).

Type: Article
Title: Fast adaptive optics scanning light ophthalmoscope retinal montaging
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/BOE.9.004317
Publisher version: http://dx.doi.org/10.1364/BOE.9.004317
Language: English
Additional information: Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.(https://creativecommons.org/licenses/by/4.0/)
Keywords: Science & Technology, Life Sciences & Biomedicine, Physical Sciences, Biochemical Research Methods, Optics, Radiology, Nuclear Medicine & Medical Imaging, Biochemistry & Molecular Biology, IMAGE
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10056657
Downloads since deposit
91Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item