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Manufacturing of graded titanium scaffolds using a novel space holder technique

Chen, Y; Kent, D; Bermingham, M; Dehghan-Manshadi, A; Wang, G; Wen, C; Dargusch, M; (2017) Manufacturing of graded titanium scaffolds using a novel space holder technique. Bioactive Materials , 2 (4) pp. 248-252. 10.1016/j.bioactmat.2017.07.001. Green open access

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Abstract

To optimize both the mechanical and biological properties of titanium for biomedical implants, a highly flexible powder metallurgy approach is proposed to generate porous scaffolds with graded porosities and pore sizes. Sugar pellets acting as space holders were compacted with titanium powder and then removed by dissolution in water before sintering. The morphology, pore structure, porosity and pore interconnectivity were observed by optical microscopy and SEM. The results show that the porous titanium has porosity levels and pore size gradients consistent with their design with gradual and smooth transitions at the interfaces between regions of differing porosities and/or pore sizes. Meanwhile, the porous titanium has high interconnectivity between pores and highly spherical pore shapes. In this article we show that this powder metallurgy processing technique, employing the novel sugar pellets as space-holders, can generate porous titanium foams with well-controlled graded porosities and pore sizes. This method has excellent potential for producing porous titanium structures for hard tissue engineering applications.

Type: Article
Title: Manufacturing of graded titanium scaffolds using a novel space holder technique
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.bioactmat.2017.07.001
Publisher version: http://dx.doi.org/10.1016/j.bioactmat.2017.07.001
Language: English
Additional information: © 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10054979
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