Prendecki, M;
Martin, L;
Tanna, A;
Antonelou, M;
Pusey, CD;
(2018)
Increased Prevalence of Thyroid Disease in Patients with Antineutrophil Cytoplasmic Antibodies–associated Vasculitis.
The Journal of Rheumatology
, 45
(5)
pp. 686-689.
10.3899/jrheum.170661.
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Abstract
Objective. Antineutrophil cytoplasmic antibodies (ANCA)–associated vasculitis (AAV) has been linked with thyroid disease as a result of antithyroid medications. We assessed the prevalence of thyroid disease in our patients with AAV. / Methods. Clinical records of 279 patients with AAV diagnosed between 1991 and 2014 were analyzed. / Results. Thyroid disease was identified in 21.5% of patients, but only 2 had previously received propylthiouracil. There was a greater proportion of female patients, patients with antimyeloperoxidase antibodies, and patients with renal disease in the group with thyroid disease. / Conclusion. Our data show a higher prevalence of thyroid disease in patients with AAV than the general population. This was not attributable to antithyroid drugs.
Type: | Article |
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Title: | Increased Prevalence of Thyroid Disease in Patients with Antineutrophil Cytoplasmic Antibodies–associated Vasculitis |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.3899/jrheum.170661 |
Publisher version: | http://dx.doi.org/10.3899/jrheum.170661 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
Keywords: | antineutrophil cytoplasmic antibodies, autoimmune disease, vasculitis, thyroid disease |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine |
URI: | https://discovery.ucl.ac.uk/id/eprint/10054251 |
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