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The role of frequent HIV testing in diagnosing HIV in men who have sex with men

Furegato, M; Mitchell, H; Ogaz, D; Woodhall, S; Connor, N; Hughes, G; Nardone, A; (2018) The role of frequent HIV testing in diagnosing HIV in men who have sex with men. HIV Medicine , 19 (2) pp. 118-122. 10.1111/hiv.12558. Green open access

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Abstract

OBJECTIVES: In the UK, quarterly HIV testing is recommended for high‐risk men who have sex with men (MSM). In this manuscript we determined the risk of being newly diagnosed with HIV in MSM by their HIV testing history, considering both the frequency and periodicity of testing. METHODS: Data on HIV incidence in MSM attending a sexual health clinic (SHC) in England in 2013−2014 with testing history (previous 2 years) were obtained from GUMCAD, the national sexually transmitted infection (STI) surveillance system in England. HIV testing patterns among MSM were defined using the frequency and periodicity of testing, based on 3 month intervals, in the year preceding the first attendance during the study period. Cox proportional hazards regression was used to determine the association between HIV testing pattern and time to HIV diagnosis with and without adjustment for demographic confounders. Analyses were stratified by risk stratum, with ‘high risk’ defined as a history of a bacterial STI in the past year. Adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) are reported. RESULTS: Among the 37 702 HIV‐negative MSM attending an SHC in 2013−2014, 1105 (3%) were diagnosed with HIV infection within 1 year of their first attendance. The probability of HIV diagnosis was highest in MSM who were tested quarterly compared with those who were not tested in the past year (aHR 2.51; 95% CI 1.33–4.74); this increased 1.8‐fold among high‐risk MSM (aHR 4.48; 95% CI 0.97–21.17). CONCLUSIONS: The probability of subsequent HIV diagnosis was greatest in high‐risk MSM who were tested most frequently. Quarterly HIV testing increased the likelihood of identifying undiagnosed HIV infection and should remain a continued recommendation for high‐risk MSM.

Type: Article
Title: The role of frequent HIV testing in diagnosing HIV in men who have sex with men
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/hiv.12558
Publisher version: https://doi.org/10.1111/hiv.12558
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: HIV diagnosis, HIV risk, HIV testing, HIV testing frequency, men who have sex with men
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10054120
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