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Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications

Isaacs, MA; Durndell, LJ; Hilton, AC; Olivi, L; Parlett, CMA; Wilson, K; Lee, AF; (2017) Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications. RSC Advances , 7 (38) pp. 23342-23347. 10.1039/c7ra03131a. Green open access

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Abstract

Silica encapsulated silver nanoparticle core–shell nanocomposites of tunable dimensions were synthesised via a one-pot reverse microemulsion route to achieve controlled release of Ag+ ions for broad spectrum antibacterial application. Silver release rates and bactericidal efficacy against Gram-positive and Gram-negative bacteria, S. aureus and P. aeruginosa respectively, were inversely proportional to nanoparticle core diameter (3–8 nm) and silica shell (7–14 nm) thickness, and readily tuned through a facile hydrothermal etching protocol employing a PVP stabiliser to introduce mesoporosity.

Type: Article
Title: Tunable Ag@SiO2 core-shell nanocomposites for broad spectrum antibacterial applications
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/c7ra03131a
Publisher version: http://dx.doi.org/10.1039/c7ra03131a
Language: English
Additional information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/10053333
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