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Adipose-Derived Stem Cells in Aesthetic Surgery

Glass, GE; Ferretti, P; (2019) Adipose-Derived Stem Cells in Aesthetic Surgery. Aesthetic Surgery Journal , 39 (4) pp. 423-438. 10.1093/asj/sjy160. Green open access

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Abstract

Adipose-derived stem cells (ADSC) have come to be viewed as a ubiquitous solution for aesthetic and reconstructive problems involving loss of tissue volume and age or radiation-induced loss of tissue pliability and vascularity. As the theoretical potential of "stem cell therapy" has captured the public imagination, so the commercial potential of novel therapies is being exploited beyond scientifically sound, hypothesis-driven paradigms and in the absence of evidence establishing clinical efficacy and safety. Moreover, with variations in methods of isolation, manipulation and reintroduction described, it is unclear how the practitioner with an interest in ASDC can harness the clinical potential in reproducible and scientifically measurable ways. This Continuing Medical Education (CME) article presents a summary of our understanding of what ADSC are, their utility within the field of aesthetic surgery and the current and future directions for adipose stem cell research.

Type: Article
Title: Adipose-Derived Stem Cells in Aesthetic Surgery
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/asj/sjy160
Publisher version: https://doi.org/10.1093/asj/sjy160
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10053029
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