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Stability of gel wax based optical scattering phantoms

Munro, PRT; Maughan Jones, C; (2018) Stability of gel wax based optical scattering phantoms. Biomedical Optics Express , 9 (8) pp. 3495-3502. 10.1364/BOE.9.003495. Green open access

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Abstract

Phantoms with tuneable optical scattering properties are essential in the development and refinement of optical based imaging techniques. Mineral oil based ‘gel wax’ phantoms are the subject of increasing interest due to their ease and speed of manufacture, non-toxic nature, ability to cast into anatomically realistic shapes, as well as their cost-effective nature of production. The addition of scatterers such as titanium dioxide powder and monodisperse silica microspheres to the gel wax allows for the creation of phantoms with a controllable optical scattering coefficient. To enable repeated use of such phantoms, the stability of the scattering properties must be determined–a property which has yet to be investigated. We present an analysis of the stability of the reduced scattering coefficient (µ’sµs’) of such phantoms over time. We conclude that due to the measurable reduction in scattering coefficient over time, gel wax phantoms embedded with silica spheres may not be suitable for repeated use over time, however gel wax-TiO2 phantoms are much more temporally stable.

Type: Article
Title: Stability of gel wax based optical scattering phantoms
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/BOE.9.003495
Publisher version: https://doi.org/10.1364/BOE.9.003495
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10052404
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