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Fluoroquinolones for Treating Tuberculosis

Kumar, K; McHugh, TD; Lipman, MCI; (2017) Fluoroquinolones for Treating Tuberculosis. The Pharmacist , 9 (5) 10.1211/CP.2017.20202555.

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Abstract

Tuberculosis (TB) remains a significant global health and socioeconomic challenge. The duration of current anti-TB therapies, the adverse effects of certain anti-TB drugs and the growing problem of drug-resistant TB on an international scale mean that it is imperative for new, effective and safe treatment regimens to be developed. Fluoroquinolones are a class of drugs that have been used in the treatment of TB for several decades. This article provides an overview of the current treatment regimens for drug-sensitive and drug-resistant TB; discusses the history, effectiveness and challenges of using fluoroquinolones in TB treatment; and considers future research priorities.

Type: Article
Title: Fluoroquinolones for Treating Tuberculosis
DOI: 10.1211/CP.2017.20202555
Publisher version: http://dx.doi.org/10.1211/CP.2017.20202555
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10052131
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