Cole, TJ;
(2018)
Optimal design for longitudinal studies to estimate pubertal height growth in individuals.
Annals of Human Biology
, 45
(4)
pp. 314-320.
10.1080/03014460.2018.1453948.
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Abstract
BACKGROUND: The SITAR model expresses individual pubertal height growth in terms of mean size, peak height velocity (PHV) and age at PHV. AIM: To use SITAR to identify the optimal time interval between measurements to summarise individual pubertal height growth. SUBJECTS AND METHODS: Heights in 3172 boys aged 9-19 years from Christ's Hospital School measured on 128 679 occasions (a median of 42 heights per boy) were analysed using the SITAR (SuperImposition by Translation And Rotation) mixed effects growth curve model, which estimates a mean curve and three subject-specific random effects. Separate models were fitted to sub-sets of the data with measurement intervals of 2, 3, 4, 6, 12 and 24 months, and the different models were compared. RESULTS: The models for intervals 2-12 months gave effectively identical results for the residual standard deviation (0.8 cm), mean spline curve (6 degrees of freedom) and random effects (correlations >0.9), showing there is no benefit in measuring height more often than annually. The model for 2-year intervals fitted slightly less well, but needed just four-to-five measurements per individual. CONCLUSIONS: Height during puberty needs to be measured only annually and, with slightly lower precision, just four biennial measurements can be sufficient.
| Type: | Article |
|---|---|
| Title: | Optimal design for longitudinal studies to estimate pubertal height growth in individuals |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/03014460.2018.1453948 |
| Publisher version: | https://doi.org/10.1080/03014460.2018.1453948 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Height, SITAR, age at peak velocity, puberty |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10051893 |
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