Castanys-Munoz, E;
Kennedy, K;
Castaneda-Gutierrez, E;
Forsyth, S;
Godfrey, KM;
Koletzko, B;
Ozanne, SE;
... Ong, KK; + view all
(2017)
Systematic review indicates postnatal growth in term infants born small-for-gestational-age being associated with later neurocognitive and metabolic outcomes.
Acta Paediatrica
, 106
(8)
pp. 1230-1238.
10.1111/apa.13868.
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Abstract
We systematically reviewed papers published in English between 1994 and October 2015 on how postnatal weight gain and growth affect neurodevelopment and metabolic outcomes in term‐born small‐for‐gestational‐age (SGA) infants. Two randomised trials reported that enriched infant formulas that promoted early growth also increased fat mass, lean mass and blood pressure (BP), but had no effect on early neurocognitive outcomes. Meanwhile, 31 observational studies reported consistent positive associations between postnatal weight gain and growth with neurocognitive outcomes, adiposity, insulin resistance and BP. // Conclusion: Few intervention studies exist, despite consistent positive associations between early growth and neurocognition in term‐born SGA infants.
| Type: | Article |
|---|---|
| Title: | Systematic review indicates postnatal growth in term infants born small-for-gestational-age being associated with later neurocognitive and metabolic outcomes |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/apa.13868 |
| Publisher version: | https://doi.org/10.1111/apa.13868 |
| Language: | English |
| Additional information: | Copyright © 2017 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Adiposity, Insulin resistance, Neurodevelopment, Postnatal growth, Small for gestational age |
| UCL classification: | UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10050866 |
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