Dalchau, N;
Szép, G;
Hernansaiz-Ballesteros, R;
Barnes, CP;
Cardelli, L;
Phillips, A;
Csikász-Nagy, A;
(2018)
Computing with biological switches and clocks.
Natural Computing
, 17
(4)
pp. 761-779.
10.1007/s11047-018-9686-x.
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Abstract
The complex dynamics of biological systems is primarily driven by molecular interactions that underpin the regulatory networks of cells. These networks typically contain positive and negative feedback loops, which are responsible for switch-like and oscillatory dynamics, respectively. Many computing systems rely on switches and clocks as computational modules. While the combination of such modules in biological systems leads to a variety of dynamical behaviours, it is also driving development of new computing algorithms. Here we present a historical perspective on computation by biological systems, with a focus on switches and clocks, and discuss parallels between biology and computing. We also outline our vision for the future of biological computing.
Type: | Article |
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Title: | Computing with biological switches and clocks |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1007/s11047-018-9686-x |
Publisher version: | http://doi.org/10.1007/s11047-018-9686-x |
Language: | English |
Additional information: | Copyright information © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
URI: | https://discovery.ucl.ac.uk/id/eprint/10050191 |
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