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A Multichannel High-Frequency Power-Isolated Neural Stimulator With Crosstalk Reduction

Jiang, D; Demosthenous, A; (2018) A Multichannel High-Frequency Power-Isolated Neural Stimulator With Crosstalk Reduction. IEEE Transactions on Biomedical Circuits and Systems , 12 (4) pp. 940-953. 10.1109/TBCAS.2018.2832541. Green open access

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Abstract

In neuroprostheses applications requiring simultaneous stimulations on a multielectrode array, electric crosstalk, the spatial interaction between electric fields from various electrodes is a major limitation to the performance of multichannel stimulation. This paper presents a multichannel stimulator design that combines high-frequency current stimulation (using biphasic charge-balanced chopped pulse profile) with a switched-capacitor power isolation method. The approach minimizes crosstalk and is particularly suitable for fully integrated realization. A stimulator fabricated in a 0.6 & #x03BC;m CMOS high-voltage technology is presented. It is used to implement a multichannel, high-frequency, power-isolated stimulator. Crosstalk reduction is demonstrated with electrodes in physiological media while the efficacy of the high-frequency stimulator chip is proven in vivo. The stimulator provides fully independent operation on multiple channels and full flexibility in the design of neural modulation protocols.

Type: Article
Title: A Multichannel High-Frequency Power-Isolated Neural Stimulator With Crosstalk Reduction
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TBCAS.2018.2832541
Publisher version: http://dx.doi.org/10.1109/TBCAS.2018.2832541
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0/
Keywords: Chopped pulse, electric crosstalk, mixed-signal integrated circuit, multichannel neural stimulator, power isolation
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Electronic and Electrical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10049968
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