Parati, G;
Agostoni, P;
Basnyat, B;
Bilo, G;
Brugger, H;
Coca, A;
Festi, L;
... Torlasco, C; + view all
(2018)
Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions.
European Heart Journal
, 39
(17)
pp. 1546-1554.
10.1093/eurheartj/ehx720.
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Abstract
Adapted from Bärtsch and Gibbs2 Physiological response to hypoxia. Life-sustaining oxygen delivery, in spite of a reduction in the partial pressure of inhaled oxygen between 25% and 60% (respectively at 2500 m and 8000 m), is ensured by an increase in pulmonary ventilation, an increase in cardiac output by increasing heart rate, changes in vascular tone, as well as an increase in haemoglobin concentration. BP, blood pressure; HR, heart rate; PaCO2, partial pressure of arterial carbon dioxide.
| Type: | Article |
|---|---|
| Title: | Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/eurheartj/ehx720 |
| Publisher version: | https://doi.org/10.1093/eurheartj/ehx720 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, CORONARY-ARTERY-DISEASE, AMBULATORY BLOOD-PRESSURE, CHRONIC MOUNTAIN-SICKNESS, CONGENITAL HEART-DISEASE, HYPOBARIC HYPOXIA, CARDIAC-FUNCTION, HEALTHY-SUBJECTS, EXERCISE, ACETAZOLAMIDE, EVEREST |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10049100 |
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