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A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules

Papadimitriou, K; Dempsey, LA; Hebden, JC; Arridge, SR; Powell, S; (2018) A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules. Biomedical Optics Express , 9 (6) pp. 2648-2663. 10.1364/BOE.9.002648. Green open access

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Abstract

We introduce a compact time-domain system for near-infrared spectroscopy using a spread spectrum technique. The proof-of-concept single channel instrument utilises a low-cost commercially available optical transceiver module as a light source, controlled by a Kintex 7 field programmable gate array (FPGA). The FPGA modulates the optical transceiver with maximum-length sequences at line rates up to 10Gb/s, allowing us to achieve an instrument response function with full width at half maximum under 600ps. The instrument is characterised through a set of detailed phantom measurements as well as proof-of-concept in vivo measurements, demonstrating performance comparable with conventional pulsed time-domain near-infrared spectroscopy systems

Type: Article
Title: A spread spectrum approach to time-domain near-infrared diffuse optical imaging using inexpensive optical transceiver modules
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/BOE.9.002648
Publisher version: http://dx.doi.org/10.1364/BOE.9.002648
Language: English
Additional information: Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10048193
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